Protect your home from unwelcome eight-legged guests with proven spider control options. This guide highlights reliable indoor and perimeter products, non-toxic traps, and barrier sprays designed to deter spiders and other common pests. Each selection includes practical usage notes to help you choose the right approach for kitchens, bathrooms, basements, and exterior foundations.
| Product | Type | Best For |
|---|---|---|
| Ortho Home Defense Insect Killer for Indoor & Perimeter2 | Aerosol/Insecticide | Immediate knockdown and long-lasting barrier indoors and around foundations |
| Ortho Home Defense Max Indoor Insect Barrier | Aerosol/Insecticide | Indoor protection for up to a year on nonporous surfaces |
| MaxGuard Spider + Insect Traps | Non-toxic glue traps | Non-chemical spider capture for ongoing indoor management |
| Wet & Forget Miss Muffet’s Revenge | Ready-to-use spray with barrier | Indoor and outdoor spider control with long-lasting barrier |
| Spider Traps for Inside Your Home (16 Traps) | Sticky traps | Safe, non-toxic interior spider trapping |
Ortho Home Defense Insect Killer for Indoor & Perimeter2

Ortho’s Home Defense Insect Killer for Indoor & Perimeter2 targets spiders along with ants, roaches, fleas, ticks, scorpions, and more. It provides a long-lasting barrier for up to 12 months on non-porous interior surfaces and can be used near doors, windows, kitchens, and bathrooms, as well as around the exterior perimeter of foundations, patios, and decks. This versatility makes it a strong first line of defense for home spider control, especially in high-traffic areas where spiders tend to appear.
Features emphasize broad insect coverage and durable indoor/outdoor protection. When applying indoors, ensure surfaces are non-porous and follow label directions for safety and effectiveness. For exterior use, apply around the foundations and entry points to reduce intrusions. This product is designed for quick knockdown and sustained control, helping reduce the likelihood of spiders finding harborage near entryways.
Ortho Home Defense Max Indoor Insect Barrier

Ortho Home Defense Max Indoor Insect Barrier provides extended protection with a Comfort Wand for easier reach. It’s designed to kill ants, roaches, spiders, fleas, and ticks, and to safeguard interiors for up to 365 days on nonporous surfaces. Use it in kitchens, bathrooms, basements, and around doors and windows, with outdoor perimeter use to create a barrier around your home. The Max formulation emphasizes longer-term indoor coverage, which helps reduce spider presence over time by limiting suitable habitats inside the home.
Considerations include the need for thorough coverage of common spider hotspots, such as corners, behind appliances, and along baseboards. While effective indoors, always adhere to ventilation and surface guidelines to avoid residue on sensitive materials. The extended reach wand is beneficial for ceilings and tall areas where spiders commonly perch.
Ortho Home Defense Insect Killer for Indoor and Perimeter Refill2

This refill version mirrors the primary Ortho defense formula, offering renewed protection against a wide range of home-invading insects, including spiders. The product aims to provide up to 12 months of protection on non-porous indoor surfaces and calls for usage around doors, windows, kitchens, and bathrooms, as well as outdoor perimeters. Refills help maintain consistent spider control without re-purchasing a full spray kit, making it a practical option for ongoing prevention.
When considering a refill, plan for thorough interior coverage and consistent reapplication on exterior perimeters to sustain an effective barrier. Pairing with an indoor barrier strategy can help minimize spider activity across multiple rooms and entry points.
MaxGuard Spider + Insect Traps

MaxGuard Spider + Insect Traps offer a non-toxic, glue-based approach to capturing spiders and other crawling insects. Each trap uses a high-adhesion adhesive and a dark interior to attract and trap spiders such as black widows, brown recluses, and hobo spiders, among others. The product emphasizes safety by avoiding insecticides, making it suitable for households with kids and pets where chemical exposure is a concern.
Key considerations include placement along walls, corners, and likely spider pathways. The non-toxic approach is ideal for ongoing monitoring, especially in living rooms, basements, and garages where spiders tend to congregate. Regularly check and replace traps to maintain efficacy and reduce spider populations over time.
Hot Shot Ant, Roach & Spider Killer

Hot Shot’s spray is designed for rapid knockdown of listed insects, including ants, roaches, and spiders, with outdoor and indoor utility. The product claims up to three months of residual effect and is suitable for kitchens, bathrooms, basements, and exterior areas around foundations and entry points. It’s a versatile option when consumers need quick control of spider activity and other pests in a single application.
When using a broad-spectrum spray like this, follow label directions for safe use around food prep areas and pets. For ongoing spider management, pair with non-chemical traps or barrier methods to reduce re-entry and prevent new spider activity in treated zones.
Wet & Forget Miss Muffet’s Revenge

Wet & Forget Miss Muffet’s Revenge combines indoor and outdoor spider control with an attached sprayer for easy application up to ten feet. It creates a barrier that lasts up to 12 months, reducing spider activity by discouraging re-infestation. The ready-to-use formula is designed for hard-to-reach areas while maintaining simplicity for homeowners who want a semi-permanent fix with minimal maintenance after application.
Users should treat entry points, corners, basements, and exterior foundation lines where spiders commonly hide. For best results, apply to dry surfaces and avoid oversaturation. The attached sprayer adds convenience for larger spaces and exterior walls, making it suitable for year-round prevention in busy homes.
Spider Traps for Inside Your Home (16 Traps)

This 16-pack of spider traps offers a safe, non-toxic approach to interior pest management. The traps are pre-baited, ultra sticky, and easy to deploy along walls, floors, and entryways. They are designed to capture a range of spiders including brown recluse and black widow varieties, as well as other crawling pests. The product is non-toxic and poison-free, making it suitable for households with children and pets who need ongoing monitoring.
Placement is key for sticky traps: position glue side up against walls and near known spider pathways. Check traps regularly and replace as needed to maintain continuous monitoring. While not a solvent or spray, these traps complement chemical controls by providing ongoing interior surveillance and reduction of spider activity.
Buying Guide
Choosing the right spider control approach depends on your space, safety concerns, and maintenance preferences. Here are practical considerations and comparisons to help you decide:
- Indoor vs. outdoor focus: For comprehensive protection, pair indoor sprays with outdoor perimeter barriers to reduce entry points. Consider traps for ongoing monitoring in living spaces.
- Chemical vs. non-toxic options: If you have children or pets, prioritize non-toxic traps and glue traps. Use chemical sprays in areas away from food and play zones and follow label directions carefully.
- Coverage and duration: Some products offer year-long protection on non-porous surfaces, while others provide shorter residual effects. Plan reapplication schedules to maintain consistent control.
- Ease of use: Comfort Wand sprayers and attached sprayers simplify reach for ceilings and corners. Glue traps require minimal maintenance but need regular checking and replacement.
- Safety and surface compatibility: Always test sprays on inconspicuous areas if unsure about material compatibility. For sensitive fabrics or electronics, use traps or barrier methods in those zones.
- Integrated approach: A combination of barrier sprays, non-toxic traps, and monitored baits provides layered protection and reduces spider harborage over time.
- Location strategy: Target common spider harborage like baseboards, under sinks, behind appliances, corners, and around door thresholds. Exterior focus should include foundations, decks, and entryways.